A homogeneous biosensor for carbohydrate antigen 153 detection in human serum based on upconversion fluorescence resonance energy transfer
Quantitative determination of carbohydrate antigen 153 (CA153) in human serum plays an important role in early diagnosis of breast cancer.In this work, a highly sensitive and selective biosensor for CA153 detection was developed based on a fluorescent resonance energy transfer (FRET) strategy, in which near-infrared (NIR)-excitable upconversion meg